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izvor podataka: crosbi

Mouse cytomegalovirus encoded immunoevasins and evolution of Ly49 receptors - sidekicks or enemies? (CROSBI ID 238376)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

Železnjak, Jelena ; Popović, Branka ; Krmpotić, Astrid ; Jonjić, Stipan ; Lisnić Juranić, Vanda Mouse cytomegalovirus encoded immunoevasins and evolution of Ly49 receptors - sidekicks or enemies? // Immunology letters, 189 (2017), 40-47. doi: 10.1016/j.imlet.2017.04.007

Podaci o odgovornosti

Železnjak, Jelena ; Popović, Branka ; Krmpotić, Astrid ; Jonjić, Stipan ; Lisnić Juranić, Vanda

engleski

Mouse cytomegalovirus encoded immunoevasins and evolution of Ly49 receptors - sidekicks or enemies?

Cytomegaloviruses (CMVs) have dedicated a large portion of their genome towards immune evasion targeting many aspects of the host immune system, particularly NK cells. However, the host managed to cope with the infection by developing multiple mechanisms to recognize viral threat and counterattack it, thus illustrating never-ending evolutionary interplay between CMV and its host. In this review, we will focus on several mechanisms of NK cell evasion by mouse CMV (MCMV), the role of host inhibitory and activating Ly49 receptors involved in the virus control and acquisition of adaptive features by NK cells as a consequence of MCMV infection

Cytomegalovirus ; Immunoevasion ; Ly49 receptors ; MHC I ; Missing-self ; NK cells

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Podaci o izdanju

189

2017.

40-47

objavljeno

0165-2478

1879-0542

10.1016/j.imlet.2017.04.007

Povezanost rada

Temeljne medicinske znanosti

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