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Pregled bibliografske jedinice broj: 869139

Porphyrin-based cationic amphiphilic photosensitisers as potential anticancer, antimicrobial and immunosuppressive agents


Malatesti, Nela; Munitic, Ivana; Jurak, Igor
Porphyrin-based cationic amphiphilic photosensitisers as potential anticancer, antimicrobial and immunosuppressive agents // Biophysical Reviews, 9 (2017), 2; 149-168 doi:10.1007/s12551-017-0257-7 (međunarodna recenzija, pregledni rad, znanstveni)


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Naslov
Porphyrin-based cationic amphiphilic photosensitisers as potential anticancer, antimicrobial and immunosuppressive agents

Autori
Malatesti, Nela ; Munitic, Ivana ; Jurak, Igor

Izvornik
Biophysical Reviews (1867-2450) 9 (2017), 2; 149-168

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
Photodynamic therapy ; Photosensitiser ; Porphyrin ; Cancer ; Infection

Sažetak
Photodynamic therapy (PDT) combines a photosensitiser, light and molecular oxygen to induce oxidative stress that can be used to kill pathogens, cancer cells and other highly proliferative cells. There is a growing number of clinically approved photosensitisers and applications of PDT, whose main advantages include the possibility of selective targeting, localised action and stimulation of the immune responses. Further improvements and broader use of PDT could be accomplished by designing new photosensitisers with increased selectivity and bioavailability. Porphyrin-based photosensitisers with amphiphilic properties, bearing one or more positive charges, are an effective tool in PDT against cancers, microbial infections and, most recently, autoimmune skin disorders. The aim of the review is to present some of the recent examples of the applications and research that employ this specific group of photosensitisers. Furthermore, we will highlight the link between their structural characteristics and PDT efficiency, which will be helpful as guidelines for rational design and evaluation of new PSs.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Biologija, Temeljne medicinske znanosti



POVEZANOST RADA


Ustanove:
Sveučilište u Rijeci - Odjel za biotehnologiju

Profili:

Avatar Url Ivana Munitić (autor)

Avatar Url Igor Jurak (autor)

Avatar Url Nela Malatesti (autor)

Poveznice na cjeloviti tekst rada:

doi https

Citiraj ovu publikaciju:

Malatesti, Nela; Munitic, Ivana; Jurak, Igor
Porphyrin-based cationic amphiphilic photosensitisers as potential anticancer, antimicrobial and immunosuppressive agents // Biophysical Reviews, 9 (2017), 2; 149-168 doi:10.1007/s12551-017-0257-7 (međunarodna recenzija, pregledni rad, znanstveni)
Malatesti, N., Munitic, I. & Jurak, I. (2017) Porphyrin-based cationic amphiphilic photosensitisers as potential anticancer, antimicrobial and immunosuppressive agents. Biophysical Reviews, 9 (2), 149-168 doi:10.1007/s12551-017-0257-7.
@article{article, year = {2017}, pages = {149-168}, DOI = {10.1007/s12551-017-0257-7}, keywords = {Photodynamic therapy, Photosensitiser, Porphyrin, Cancer, Infection}, journal = {Biophysical Reviews}, doi = {10.1007/s12551-017-0257-7}, volume = {9}, number = {2}, issn = {1867-2450}, title = {Porphyrin-based cationic amphiphilic photosensitisers as potential anticancer, antimicrobial and immunosuppressive agents}, keyword = {Photodynamic therapy, Photosensitiser, Porphyrin, Cancer, Infection} }
@article{article, year = {2017}, pages = {149-168}, DOI = {10.1007/s12551-017-0257-7}, keywords = {Photodynamic therapy, Photosensitiser, Porphyrin, Cancer, Infection}, journal = {Biophysical Reviews}, doi = {10.1007/s12551-017-0257-7}, volume = {9}, number = {2}, issn = {1867-2450}, title = {Porphyrin-based cationic amphiphilic photosensitisers as potential anticancer, antimicrobial and immunosuppressive agents}, keyword = {Photodynamic therapy, Photosensitiser, Porphyrin, Cancer, Infection} }

Časopis indeksira:


  • Scopus


Uključenost u ostale bibliografske baze podataka::


  • CA Search (Chemical Abstracts)
  • INSPEC


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