Napredna pretraga

Pregled bibliografske jedinice broj: 868772

Fatty acid profile in maternal and fetal blood of pregnant women with type 1 diabetes mellitus


Herman, Mislav; Djelmis, Josip; Berberovic, Edina; Horvaticek, Marina; Ivanisevic, Marina.
Fatty acid profile in maternal and fetal blood of pregnant women with type 1 diabetes mellitus // 9th International DIP Symposium on Diabetes, Hypertension, Metabolic Syndrome & Pregnancy
Barcelona, Španjolska, 2017. str. 1-1 (predavanje, međunarodna recenzija, sažetak, znanstveni)


Naslov
Fatty acid profile in maternal and fetal blood of pregnant women with type 1 diabetes mellitus

Autori
Herman, Mislav ; Djelmis, Josip ; Berberovic, Edina ; Horvaticek, Marina ; Ivanisevic, Marina.

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
9th International DIP Symposium on Diabetes, Hypertension, Metabolic Syndrome & Pregnancy / - , 2017, 1-1

Skup
9th International DIP Symposium on Diabetes, Hypertension, Metabolic Syndrome & Pregnancy

Mjesto i datum
Barcelona, Španjolska, 08.-12.03.2017

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
type 1 diabetes mellitus, fatty acids profile, total lipids, maternal and umbilical vein blood samples

Sažetak
Objective: To investigate the impact of type 1 diabetes mellitus (T1DM) on the fatty acids profile in the maternal and umbilical vein blood. Methods: 60 pregnant women who delivered eutrophic infants (30 pregnant women with T1DM and 30 healthy pregnant women) were included in the study. Immediately after birth maternal and umbilical vein (UV) blood samples were collected. After lipid extraction, gas chromatography was obtained in order to obtain profile of fatty acids in total lipids of maternal and UV serum. Results: Infants of mothers with T1DM had a significantly higher concentration of glucose, C- peptide, leptin, higher ponderal index and higher insulin resistance than infants in the control group (p 0.001). The total concentration of fatty acids in maternal serum did not differ between the experimental groups (p = 0.122). The total concentration of fatty acids in the UV serum was statistically significantly higher in infants born to diabetic mothers compared to the control group (2243.3 ± 177.1: 1360.0 ± 138.0 ; p 0.001). Comparing individual profile of fatty acids in maternal serum of two studied groups, we didn`t find statistically significant difference. When comparing individual fatty acids in the serum of UV, statistically significant differences in almost every fatty acid, except for gamma- linolenic and docosahexaenoic fatty acid (C18: 3n-3 and DHA) was found. Conclusion: Good metabolic control of pregnant women with T1DM has resulted in small and insignificant changes in the maternal blood fatty acids profile and delivery of eutrophic newborns although total concentration of fatty acids in UV serum was still higher when compared to the values from infants born to the healthy mothers.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti



POVEZANOST RADA


Projekt / tema
108-1080401-0385 - Dijabetes i metabolički sindrom nakon prethodnog gestacijskog dijabetesa (Marina Ivanišević, )
108-1080401-0386 - Metaboličke i endokrine promjene u dijabetičnih trudnica (Josip Đelmiš, )

Ustanove
Medicinski fakultet, Zagreb

Citiraj ovu publikaciju

Herman, Mislav; Djelmis, Josip; Berberovic, Edina; Horvaticek, Marina; Ivanisevic, Marina.
Fatty acid profile in maternal and fetal blood of pregnant women with type 1 diabetes mellitus // 9th International DIP Symposium on Diabetes, Hypertension, Metabolic Syndrome & Pregnancy
Barcelona, Španjolska, 2017. str. 1-1 (predavanje, međunarodna recenzija, sažetak, znanstveni)
Herman, M., Djelmis, J., Berberovic, E., Horvaticek, M. & Ivanisevic, M. (2017) Fatty acid profile in maternal and fetal blood of pregnant women with type 1 diabetes mellitus. U: 9th International DIP Symposium on Diabetes, Hypertension, Metabolic Syndrome & Pregnancy.
@article{article, year = {2017}, pages = {1-1}, keywords = {type 1 diabetes mellitus, fatty acids profile, total lipids, maternal and umbilical vein blood samples}, title = {Fatty acid profile in maternal and fetal blood of pregnant women with type 1 diabetes mellitus}, keyword = {type 1 diabetes mellitus, fatty acids profile, total lipids, maternal and umbilical vein blood samples}, publisherplace = {Barcelona, \v{S}panjolska} }