engleski

The impact of the IADPSG diagnostic criteria on the prevalence of GDM compared to NICE criteria

Objective. To investigate the impact of the International Association of Diabetic Pregnancy Study Group (IADPSG) diagnostic criteria on the prevalence of gestational diabetes mellitus (GDM) and OD (overt diabetes) compared to the UK’s National Institute for Health and Care Excellence criteria (NICE) and to evaluate the frequency of obese women, cesarean deliveries, hypertensive disorders in the pregnant cohort with FPG levels 5.1-5.5mmol/l. Methods. A retrospective observational study was undertaken at Department of Obstetrics and Gynecology Hospital Medical Center Zagreb, Croatia, from January 1, 2012 to December 31, 2014. Results. Data from 4, 646 women who underwent diagnostic 2 hour OGTT were obtained. According to the NICE criteria 17.8% women had GDM and according to IADPSG criteria 23.1% women had GDM and 1.1% had OD. There were 8.8% women whose FPG levels were 5.1-5.5mmol/l and 2-h OGTT value lower than 7.8mmol/l. Women who had FPG levels 5.1-5.5mmol/l had higher the odds of having large-for-gestational-age (LGA) newborns, OR 3.7 (95% CI 1.7-4.6) and cesarean delivery OR 1.8 (95% CI 1.3-2.3) compared to women in the control group. Conclusion. Our results confirm that women with FPG levels 5.1- 5.5mmol/l are at increased risk of adverse maternal and perinatal outcome.

gestational diabetes mellitus, overt diabetes, IADPSG, NICE, diagnostic criteria

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