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Pregled bibliografske jedinice broj: 866241

Mitotic Spindle Assembly : Building the Bridge between Sister K-Fibers


Simunić, Juraj; Tolić, Iva Marija
Mitotic Spindle Assembly : Building the Bridge between Sister K-Fibers // Trends in biochemical sciences, 41 (2016), 10; 824-833 doi:10.1016/j.tibs.2016.07.004 (međunarodna recenzija, pregledni rad, znanstveni)


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Naslov
Mitotic Spindle Assembly : Building the Bridge between Sister K-Fibers

Autori
Simunić, Juraj ; Tolić, Iva Marija

Izvornik
Trends in biochemical sciences (0968-0004) 41 (2016), 10; 824-833

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
chromosome congression ; kinetochores ; mitosis ; overlap microtubules ; prometaphase ; spindle formation

Sažetak
The mitotic spindle performs the task of physically dividing the genetic material between the newly formed daughter cells. To achieve this, bundles of microtubules and associated proteins orchestrate forces that spatially organize and then separate the chromosomes. In the classic view of the spindle, the kinetochore microtubules (k-fibers) are tensed and, thus, straight, whereas interpolar bundles are curved and do not interact with k-fibers close to the spindle equator. The updated view of the spindle depicts k- fibers as curved and interacting with newly identified interpolar bundles, called bridging fibers, along their length. In this Opinion, we propose and discuss scenarios for the origin of this structure in the context of known spindle assembly mechanisms.

Izvorni jezik
Engleski

Znanstvena područja
Biologija



POVEZANOST RADA


Ustanove
Institut "Ruđer Bošković", Zagreb

Profili:

Avatar Url Iva Marija Tolić (autor)

Avatar Url Juraj Simunić (autor)

Citiraj ovu publikaciju

Simunić, Juraj; Tolić, Iva Marija
Mitotic Spindle Assembly : Building the Bridge between Sister K-Fibers // Trends in biochemical sciences, 41 (2016), 10; 824-833 doi:10.1016/j.tibs.2016.07.004 (međunarodna recenzija, pregledni rad, znanstveni)
Simunić, J. & Tolić, I. (2016) Mitotic Spindle Assembly : Building the Bridge between Sister K-Fibers. Trends in biochemical sciences, 41 (10), 824-833 doi:10.1016/j.tibs.2016.07.004.
@article{article, year = {2016}, pages = {824-833}, DOI = {10.1016/j.tibs.2016.07.004}, keywords = {chromosome congression, kinetochores, mitosis, overlap microtubules, prometaphase, spindle formation}, journal = {Trends in biochemical sciences}, doi = {10.1016/j.tibs.2016.07.004}, volume = {41}, number = {10}, issn = {0968-0004}, title = {Mitotic Spindle Assembly : Building the Bridge between Sister K-Fibers}, keyword = {chromosome congression, kinetochores, mitosis, overlap microtubules, prometaphase, spindle formation} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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