engleski

Antimicrobial resistance of pathogens causing urinary tract infections

Local research of pathogens causing clinical syndromes and their resistance to antibiotics is important for determination and constant reassessment of empirical antimicrobial therapy. The aim of this paper was to determine the resistance of pathogens causing urinary tract infections to most commonly administered antibiotics. In the period from 01/01/1996 to 31/12/2000, a total of 3031 bacterial strains isolated from urine samples of patients treated at the Outpatient Clinic for Urogenital Infections were analyzed. The most frequently isolated bacteria were Escherichia coli (50.44%), Entreococcus spp. (23.04%), Streptococcus agalactiae (9.08%), Proteus mirabilis (6.78%) and Klebsiella pneumoniae (5.19%). Of the 1525 E.coli strains, 20.02% were resistant to co-trimoxazole, 47.25% to amoxycillin, 10.18% to first generation cephalosporins, 1.48% to second generation cephalosporins, and 7.05% to fluoroquinolones. In this 5 years period, E.coli has not developed a significantly different susceptibility to either one tested antimicrobial drug, while Enterococcus spp showed a significant decrease in resistance to gentamicin, nitrofurantoin and erythromycin.

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