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Pregled bibliografske jedinice broj: 857086

Macro- and microelements in the rat liver, kidneys, and brain tissues ; sex differences and effect of blood removal by perfusion in vivo


Orct, Tatjana; Jurasović, Jasna; Micek, Vedran; Karaica, Dean; Sabolić, Ivan
Macro- and microelements in the rat liver, kidneys, and brain tissues ; sex differences and effect of blood removal by perfusion in vivo // Journal of trace elements in medicine and biology, 40 (2017), 104-111 doi:10.1016/j.jtemb.2016.12.015 (međunarodna recenzija, članak, znanstveni)


Naslov
Macro- and microelements in the rat liver, kidneys, and brain tissues ; sex differences and effect of blood removal by perfusion in vivo

Autori
Orct, Tatjana ; Jurasović, Jasna ; Micek, Vedran ; Karaica, Dean ; Sabolić, Ivan

Izvornik
Journal of trace elements in medicine and biology (0946-672X) 40 (2017); 104-111

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Gender differences ; ICP-MS ; Macronutrients ; Micronutrients ; Rat organs ; Trace elements

Sažetak
Concentrations of macro- and microelements in animal organs indicate the animal health status and represent reference data for animal experiments. Their levels in blood and tissues could be different between sexes, and could be different with and without blood in tissues. To test these hypotheses, in adult female and male rats the concentrations of various elements were measured in whole blood, blood plasma, and tissues from blood-containing (nonperfused) and blood-free liver, kidneys, and brain (perfused in vivo with an elements-free buffer). In these samples, 6 macroelements (Na, Mg, P, S, K, Ca) and 14 microelements (Fe, Mn, Co, Cu, Zn, Se, I, As, Cd, Hg, Pb, Li, B, Sr) were determined by inductively coupled plasma mass spectrometry following nitric acid digestion. In blood and plasma, female- or male-dominant sex differences were observed for 6 and 5 elements, respectively. In nonperfused organs, sex differences were observed for 3 (liver, brain) or 9 (kidneys) elements, whereas in perfused organs, similar differences were detected for 9 elements in the liver, 5 in the kidneys, and none in the brain. In females, perfused organs had significantly lower concentrations of 4, 5, and 2, and higher concentrations of 10, 4, and 7 elements, respectively, in the liver, kidneys, and brain. In males, perfusion caused lower concentrations of 4, 7, and 2, and higher concentrations of 1, 1, and 7 elements, respectively, in the liver, kidneys, and brain. Therefore, the residual blood in organs can significantly influence tissue concentrations of various elements and their sex-dependency.

Izvorni jezik
Engleski

Znanstvena područja
Javno zdravstvo i zdravstvena zaštita, Veterinarska medicina



POVEZANOST RADA


Ustanove
Institut za medicinska istraživanja i medicinu rada, Zagreb

Profili:

Avatar Url Jasna Jurasović (autor)

Avatar Url Ivan Sabolić (autor)

Avatar Url Tatjana Orct (autor)

Avatar Url Dean Karaica (autor)

Citiraj ovu publikaciju

Orct, Tatjana; Jurasović, Jasna; Micek, Vedran; Karaica, Dean; Sabolić, Ivan
Macro- and microelements in the rat liver, kidneys, and brain tissues ; sex differences and effect of blood removal by perfusion in vivo // Journal of trace elements in medicine and biology, 40 (2017), 104-111 doi:10.1016/j.jtemb.2016.12.015 (međunarodna recenzija, članak, znanstveni)
Orct, T., Jurasović, J., Micek, V., Karaica, D. & Sabolić, I. (2017) Macro- and microelements in the rat liver, kidneys, and brain tissues ; sex differences and effect of blood removal by perfusion in vivo. Journal of trace elements in medicine and biology, 40, 104-111 doi:10.1016/j.jtemb.2016.12.015.
@article{article, year = {2017}, pages = {104-111}, DOI = {10.1016/j.jtemb.2016.12.015}, keywords = {Gender differences, ICP-MS, Macronutrients, Micronutrients, Rat organs, Trace elements}, journal = {Journal of trace elements in medicine and biology}, doi = {10.1016/j.jtemb.2016.12.015}, volume = {40}, issn = {0946-672X}, title = {Macro- and microelements in the rat liver, kidneys, and brain tissues ; sex differences and effect of blood removal by perfusion in vivo}, keyword = {Gender differences, ICP-MS, Macronutrients, Micronutrients, Rat organs, Trace elements} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Uključenost u ostale bibliografske baze podataka:


  • TOXLINE


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