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Pregled bibliografske jedinice broj: 854404

Wnt signaling is activated in human astrocytomas


Pećina-Šlaus, Nives; Kafka, Anja; Tomas, Davor; Marković, Leon; Varošanec, Ana Maria; Bačić, Mateja; Njirić, Niko
Wnt signaling is activated in human astrocytomas // Wnt Meeting 2016 EMBO Conference
Brno, Češka, 2016. (poster, međunarodna recenzija, sažetak, znanstveni)


Naslov
Wnt signaling is activated in human astrocytomas

Autori
Pećina-Šlaus, Nives ; Kafka, Anja ; Tomas, Davor ; Marković, Leon ; Varošanec, Ana Maria ; Bačić, Mateja ; Njirić, Niko

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Wnt Meeting 2016 EMBO Conference / - , 2016

Skup
Wnt Meeting 2016 EMBO Conference

Mjesto i datum
Brno, Češka, 14-17.09.2016

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Wnt signaling ; human astrocytomas

Sažetak
Molecular and genetic landscapes of human astrocytic brain tumors still need elucidation. In the present study key players of Wnt signaling, beta-catenin (CTNNB1), TCF1 and LEF1, adenomatous polyposis coli (APC), AXIN1, SFRP3 and dishevelleds 1, 2 and 3 (DVL1, DVL2, DVL3) were investigated in human astrocytic tumors. Genetic changes were tested by PCR/loss of heterozygosity (LOH), microsatellite instability (MSI) and heteroduplex methods. Protein expressions were investigated by immunohistochemistry.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti



POVEZANOST RADA


Ustanove
Medicinski fakultet, Zagreb