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Cholinesterase-inhibitory activity of essential oils


Burčul, Franko; Radan, Mila; Politeo, Olivera; Blažević, Ivica.
Cholinesterase-inhibitory activity of essential oils // Advances in Chemistry Research. Volume 37. / Taylor, James C. (ur.).
New York: Nova Science Publishers Inc., 2017. str. 15-87


Naslov
Cholinesterase-inhibitory activity of essential oils

Autori
Burčul, Franko ; Radan, Mila ; Politeo, Olivera ; Blažević, Ivica.

Vrsta, podvrsta i kategorija rada
Poglavlja u knjigama, ostalo

Knjiga
Advances in Chemistry Research. Volume 37.

Urednik/ci
Taylor, James C.

Izdavač
Nova Science Publishers Inc.

Grad
New York

Godina
2017

Raspon stranica
15-87

ISBN
978-1-53611-041-8

Ključne riječi
essential oils, terpenes, terpenoids, phenylpropanoids, acetylcholinesterase, butyrylcholinesterase

Sažetak
Essential oils (EOs) are a complex mixtures containing volatile secondary metabolites with various structures (terpenes, terpenoids, phenylpropanoids, and others). Their roles in plants vary from attracting pollinators to a defense against insects, food storage, and adaptations to harsh climate. Since ancient times, EOs are recognized for their medicinal value, representing a valuable source of biologically active compounds. EOs possess various activities including: antimicrobial, antiviral, antioxidant, antitumor, etc. They have also been used as perfumes, flavors for foods and beverages, remedies for the body and mind, and continue to be of paramount importance to date. Having a small molecular weight and lipid solubility, EO constituents possess the ability to pass the blood-brain barrier. Given the complexity of their chemical composition and ability to enter the brain, EOs and their constituents offer a promising strategy for the treatment of various neurological disorders. Alzheimer's disease has been responsible for more than 50% of neurological diseases among persons over the age of 65 years. EOs are found to be potential acetylcholinesterase and butyrylcholinesterase inhibitors, two enzymes which still represent the only pharmacoterapeutic targets against Alzheimer's disease. The purpose of this chapter is to provide an overview of the current knowledge about the activity of the EOs with defined chemical composition, tested against cholinesterases and to identify the ones that could be potentially used in Alzheimer's treatment.

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA


Projekt / tema
HRZZ-IP-2014-09-6897 - Istraživanje bioaktivnih spojeva iz dalmatinskogbilja: njihov antioksidacijski karakter i utjecaj na enzimsku inhibiciju i zdravlje (Mladen Miloš, )

Ustanove
Kemijsko-tehnološki fakultet, Split

Profili:

Avatar Url Mila Radan (autor)

Avatar Url Olivera Politeo (autor)

Avatar Url Ivica Blažević (autor)

Avatar Url Franko Burčul (autor)

Citiraj ovu publikaciju

Burčul, Franko; Radan, Mila; Politeo, Olivera; Blažević, Ivica.
Cholinesterase-inhibitory activity of essential oils // Advances in Chemistry Research. Volume 37. / Taylor, James C. (ur.).
New York: Nova Science Publishers Inc., 2017. str. 15-87
Burčul, F., Radan, M., Politeo, O. & Blažević, I. (2017) Cholinesterase-inhibitory activity of essential oils. U: Taylor, J. (ur.) Advances in Chemistry Research. Volume 37.. New York, Nova Science Publishers Inc., str. 15-87.
@inbook{inbook, editor = {Taylor, J.}, year = {2017}, pages = {15-87}, keywords = {essential oils, terpenes, terpenoids, phenylpropanoids, acetylcholinesterase, butyrylcholinesterase}, isbn = {978-1-53611-041-8}, title = {Cholinesterase-inhibitory activity of essential oils}, keyword = {essential oils, terpenes, terpenoids, phenylpropanoids, acetylcholinesterase, butyrylcholinesterase}, publisher = {Nova Science Publishers Inc.}, publisherplace = {New York} }