Putting the X in Expression: Tooth Crown Morphology and Chromosome Number (CROSBI ID 642047)
Prilog sa skupa u časopisu | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Maier, Christopher ; Dumančić, Jelena ; Brkić, Hrvoje ; Kaić, Zvonimir ; Scott, G. Richard
engleski
Putting the X in Expression: Tooth Crown Morphology and Chromosome Number
Researchers have noted differences in tooth size between individuals with a normal chromosomal complement and those with Turner (XO) and Klinefelter’s (XXY) syndromes. Tooth size is decreased in individuals lacking an X chromosome but the effects are more variable when there is an extra X chromosome. How the number of X chromosomes affects tooth crown morphology is less well known. To evaluate the impact of sex chromosome number on morphology, observations were made on individuals with Turner syndrome, Klinefelter’s syndrome, and a control group at the University of Zagreb School of Dental Medicine. Trait expression was scored following ASUDAS for a standard set of maxillary and mandibular crown traits. For the control group, sexes were pooled because crown traits show little or no sex dimorphism. Chi- square tests and Fisher’s exact test with the Bonferroni correction for multiple comparisons were used to evaluate the differences among the three samples. Results show Turner syndrome individuals are significantly different from either the control sample, the Klinefelter’s syndrome sample, or both for UI1 and UI2 shoveling, UM1 and UM2 hypocones, and LP1 and LP2 multiple lingual cusps. For these traits, the pattern may be related to tooth size as individuals with Turner syndrome exhibit significantly lower grades of expression. The majority of crown traits did not show significant differences among the three samples. Assessing which traits are affected by variable numbers of X chromosomes will help further our understanding of the role sex chromosomes play in the development of tooth size and morphology.
chromosome X ; Turner syndrome ; Klinefelter syndrome ; ASUDAS
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Podaci o prilogu
216-217.
2016.
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objavljeno
Podaci o matičnoj publikaciji
American journal of physical anthropology
John Wiley & Sons
0002-9483
1096-8644
Podaci o skupu
85th Annual Meeting of the American Association of Physical Anthropologists
poster
12.04.2016-16.04.2016
Atlanta (GA), Sjedinjene Američke Države
Povezanost rada
Dentalna medicina