De novo assembly using long error-prone reads (CROSBI ID 407810)
Ocjenski rad | diplomski rad
Podaci o odgovornosti
Kostelac, Mario
Šikić, Mile
engleski
De novo assembly using long error-prone reads
Assembling genomes from long error-prone reads without error correction seems like a promising method. The thesis shows that layout methods used for assembling genomes from short reads can be utilized for assembling from long error- prone reads, if coupled with new methods for eliminating the noise from a dataset. Methods are validated with two datasets of Escherichia coli (PacBio and Oxford Nanopore Technologies). Results are compared with results of the miniasm assembler.
De novo assembly; PacBio; Oxford Nanopore Technologies; layout
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Podaci o izdanju
59
01.02.2016.
obranjeno
Podaci o ustanovi koja je dodijelila akademski stupanj
Fakultet elektrotehnike i računarstva
Zagreb