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Volanesorsen Antisense oligonucleotide targeting ApoC-III Treatment of familial chylomicronemia syndrome Treatment of hypertriglyceridemia Treatment of lipodystrophy

Elevated triglycerides have been recognized as an important factor of many pathological states and lowering them has become more and more a relevant factor in taking care of patients who suffer from the disease, obesity, metabolic syndrome and diabetes type 2. Hypertriglyceridemia is also associated with some rare diseases like familial chylomicronemia syndrome and familial partial lipodystrophy that currently have limited therapeutic options.

Volanesorsen ; ISIS-304801 ; Apolipoprotein C-III ; Monoclonal antibody ; Triglycerides ; Cardiovascular risk

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