hrvatski

Zastupljenost i obilježja epilepsije u djece s cerebralnom paralizom

Surveillance of Cerebral Palsy in Europe (SCPE) je funkcionalna klasifikacija cerebralne paralize (CP). Osim osnovnih tipova (spastični, diskinetski, ataktični) i podtipova (bilateralni/unilateralni spastični, distoni i koreo-atetotski), registrira i pridružena odstupanja: epilepsiju, poremećaje senzorike te kognitivni razvoj. Prikazujemo zastupljenost i obilježja epilepsije u djece s CP u Hrvatskom SCPE registru. Istraživanjem su obuhvaćena djeca rođena 2006. i 2007. uključena u Hrvatski SCPE registar. Od ukupno 75.024 živorođenih u 16 županija 2006. i u 18 županija 2007., 156 djece je razvilo CP (prevalencija 2, 08‰). Od 156 djece s CP, 90% je imalo spastičnu CP (bilateralnu 60%, unilateralnu 30%), diskinetskih je bilo 9%, a ataktičnih 1%. Epilepsiju je imalo 48% djece s CP, a 83% je na antiepileptičkoj terapiji. Najčešće se epilepsija javila tijekom prve godine, u 37% djece ; u dobi 2.-4. godine se javljala u 8% djece godišnje, a u starijih od četvrte godine u još ukupno 11% djece. U najvećem broju epilepsija je bila prisutna u djece s bilateralnom spastičnom CP, u 47 (50%), a u djece s unilateralnom u 24 (34%). Iako je diskinetska CP zastupljena sa svega 9% djece s CP, njih 10, odnosno 72%, je razvilo epilepsiju. Zaključno, u Hrvatskom SCPE registru 48% djece je razvilo epilepsiju od kojih je u 83% aktivna. Broj djece s epilepsijom je najveći u djece s bilateralnom spastičnom CP, no najveći udio epilepsije je u diskinetskoj CP. Početak epilepsije je najčešći tijekom prve godine. Veliki postotak epilepsije u djece s CP, njena aktivnost i rani početak zahtijevaju pojačani nadzor neuropedijatra. --- Surveillance of Cerebral Palsy in Europe (SCPE) is functional classification of cerebral palsy (CP). Apart basic types (spastic, dyskinetic, ataxic) and subtypes (bilateral/unilateral spastic, dystonic and choreo-athetotic), it also registers associated impairments – epilepsy, sensory and cognitive impairments. We present prevalence and characteristics of epilepsy in children with CP in Croatian SCPE register. This study comprises children born 2006 and 2007 enrolled in Croatian SCPE register. Out of 75, 024 liveborn 2006 in 16 and 2007 in 18 counties, 156 children developed CP (prevalence 2.08‰). Among 156 children with CP, 90% had spastic CP (bilateral 60%, unilateral 30%), dyskinetic CP had 9% and ataxic 1%. Out of total number of CP children, 48% had epilepsy, among whom 83% received antiepileptic therapy. Onset of epilepsy in 37% children was during first year, at ages 2nd-4th in 8% per year and after 4th year of life in total of 11% of children. In most cases epilepsy occurred in children with bilateral spastic CP, in 47 (50%), while in children with unilateral in 34%. Although dyskinetic CP was represented with only 9% of CP children, 10 of them, 72%, developed epilepsy. In conclusion, in Croatian SCPE register 48% children had epilepsy among which in 83% was active. Number of children with epilepsy was highest in children with bilateral spastic CP, but largest proportion of epilepsy was in dyskinetic CP. Onset of epilepsy was most frequent during first year. High percentage of epilepsy in children with CP, its activity and early onset demand intensive neuropediatric monitoring.

cerebralna paraliza ; epilepsija ; zastupljenost ; obilježja

nije evidentirano

engleski

Prevalence and characteristics of epilepsy in children with cerebral palsy

Surveillance of Cerebral Palsy in Europe (SCPE) je funkcionalna klasifikacija cerebralne paralize (CP). Osim osnovnih tipova (spastični, diskinetski, ataktični) i podtipova (bilateralni/unilateralni spastični, distoni i koreo-atetotski), registrira i pridružena odstupanja: epilepsiju, poremećaje senzorike te kognitivni razvoj. Prikazujemo zastupljenost i obilježja epilepsije u djece s CP u Hrvatskom SCPE registru. Istraživanjem su obuhvaćena djeca rođena 2006. i 2007. uključena u Hrvatski SCPE registar. Od ukupno 75.024 živorođenih u 16 županija 2006. i u 18 županija 2007., 156 djece je razvilo CP (prevalencija 2, 08‰). Od 156 djece s CP, 90% je imalo spastičnu CP (bilateralnu 60%, unilateralnu 30%), diskinetskih je bilo 9%, a ataktičnih 1%. Epilepsiju je imalo 48% djece s CP, a 83% je na antiepileptičkoj terapiji. Najčešće se epilepsija javila tijekom prve godine, u 37% djece ; u dobi 2.-4. godine se javljala u 8% djece godišnje, a u starijih od četvrte godine u još ukupno 11% djece. U najvećem broju epilepsija je bila prisutna u djece s bilateralnom spastičnom CP, u 47 (50%), a u djece s unilateralnom u 24 (34%). Iako je diskinetska CP zastupljena sa svega 9% djece s CP, njih 10, odnosno 72%, je razvilo epilepsiju. Zaključno, u Hrvatskom SCPE registru 48% djece je razvilo epilepsiju od kojih je u 83% aktivna. Broj djece s epilepsijom je najveći u djece s bilateralnom spastičnom CP, no najveći udio epilepsije je u diskinetskoj CP. Početak epilepsije je najčešći tijekom prve godine. Veliki postotak epilepsije u djece s CP, njena aktivnost i rani početak zahtijevaju pojačani nadzor neuropedijatra. --- Surveillance of Cerebral Palsy in Europe (SCPE) is functional classification of cerebral palsy (CP). Apart basic types (spastic, dyskinetic, ataxic) and subtypes (bilateral/unilateral spastic, dystonic and choreo-athetotic), it also registers associated impairments – epilepsy, sensory and cognitive impairments. We present prevalence and characteristics of epilepsy in children with CP in Croatian SCPE register. This study comprises children born 2006 and 2007 enrolled in Croatian SCPE register. Out of 75, 024 liveborn 2006 in 16 and 2007 in 18 counties, 156 children developed CP (prevalence 2.08‰). Among 156 children with CP, 90% had spastic CP (bilateral 60%, unilateral 30%), dyskinetic CP had 9% and ataxic 1%. Out of total number of CP children, 48% had epilepsy, among whom 83% received antiepileptic therapy. Onset of epilepsy in 37% children was during first year, at ages 2nd-4th in 8% per year and after 4th year of life in total of 11% of children. In most cases epilepsy occurred in children with bilateral spastic CP, in 47 (50%), while in children with unilateral in 34%. Although dyskinetic CP was represented with only 9% of CP children, 10 of them, 72%, developed epilepsy. In conclusion, in Croatian SCPE register 48% children had epilepsy among which in 83% was active. Number of children with epilepsy was highest in children with bilateral spastic CP, but largest proportion of epilepsy was in dyskinetic CP. Onset of epilepsy was most frequent during first year. High percentage of epilepsy in children with CP, its activity and early onset demand intensive neuropediatric monitoring.

cerebral palsy ; epilepsy ; prevalence ; characteristics

nije evidentirano