Napredna pretraga

Pregled bibliografske jedinice broj: 841068

Methicillin-resistant Staphylococcus aureus in North-east Croatia


Pastuović, Tajana; Perić, Magdalena; Bošnjak, Zinka; Ružman, Nataša; Reisz Majić, Patricia; Talapko, Jasminka; Atalić, Vlasta; Loci-Zvocak, Snježana; Vuković, Dubravka
Methicillin-resistant Staphylococcus aureus in North-east Croatia // Acta Medica Academica, 44 (2015), 1; 10-17 doi:10.5644/ama2006-124.122 (međunarodna recenzija, članak, znanstveni)


Naslov
Methicillin-resistant Staphylococcus aureus in North-east Croatia

Autori
Pastuović, Tajana ; Perić, Magdalena ; Bošnjak, Zinka ; Ružman, Nataša ; Reisz Majić, Patricia ; Talapko, Jasminka ; Atalić, Vlasta ; Loci-Zvocak, Snježana ; Vuković, Dubravka

Izvornik
Acta Medica Academica (1840-2879) 44 (2015), 1; 10-17

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Staphylococcus aureus  MRSA  Healthcare-associated infection

Sažetak
Objective. The aim of this 5-year study was to determine the frequen- cy and antibiotic susceptibility of methicillin-resistant Staphylococcus aureus ( MRSA)-related infections at Osijek Clinical Hospital. Ma - terials and methods. A total of 1987 staphylococci-infected clinical isolates were collected and analysed at the Microbiology Department of the Public Health Institute of Osijek-Baranja County. Results. Be - tween 2008 and 2012, the average rate of MRSA-related infections in staphylococci-infected patients was 27.4%. The proportion of MRSA- related infections on all Staphylococcus aureus (S. aureus) isolates from clinical specimens showed a decreasing trend, from 32.6% in 2008 to 25.5% in 2012. MRSA-related infections were mostly detected in wound swabs (50.6%) and aspirates (28.8%) of patients hospitalized in the surgical (49.8%) and intensive care units (27.9%). MRSA-relat- ed infection showed an increase compared to S. aureus -infections in samples of wounds and aspirates in 2011 and 2012 (57.9%/34.9% and 35.2%/16.3%, respectively). The majority of strains of MRSA-related infections were resistant to several antibiotics, including erythromycin and clindamycin, where susceptibility were less than 10%. All MRSA isolates were susceptible to vancomycin, teicoplanin and linezolid. Therefore, antibiotic therapies for MRSA infections include vancomy- cin, teicoplanin and linezolid, but microbiological diagnostics need to be performed in order to know when the use of glycopeptides and oxazolidinones is indicated. Conclusion. Our results suggest that ap- propriate prevention measures, combined with the more rational use of antibiotics are crucial to reduce the spread of MRSA-related infec- tion in healthcare settings. Further monitoring is necessary of the in- cidence and antibiotic susceptibility of MRSA-related infections in our community.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Uključenost u ostale bibliografske baze podataka:


  • MEDLINE


Citati