engleski

Quick estimation of dietary exposure to heterocyclic aromatic amines and acrylamide in a Croatian female population

Acrylamide (AA) and heterocyclic aromatic amines (HAA) are formed in food in Maillard- type reactions. These products are common in the daily diet worldwide and are suspected to contribute to a higher risk of cancer. This study used a quick interview and calculation for a preliminary estimation of dietary exposure to heterocyclic aromatic amines MeIQx (2-amino-3, 8- dimethylimidazo[4, 5-f]quinoxaline) and PhIP (2- amino-1-methyl-6-phenylimidazo[4, 5- b]pyridine), as well as AA in 94 adult women from eastern Croatia. Subjects were administered a questionnaire to obtain information on their anthropometric and socio- economic characteristics, and on their dietary habits. Intake of main sources of HAA and AA was determined and combined with literature data on their food levels. Both high and low estimates were calculated by the use of maximum and minimum published levels. The low estimate approach produced mean daily exposures to MeIQx (0.93 ± 0.77 ng kg-1 body weight, bw) and PhIP (2.34 ± 2.49 ng kg-1 bw), as well as a provisional total HAA intake of 4.43 ng∙kg-1 bw per day, that fit better within the range of results reported by other authors. Similarly, the low estimate of AA daily exposure (122.66 ± 60.00 ng kg-1 bw) was below the lower end of the range determined by the European Food Safety Authority but more plausible considering other published levels.

acrylamide ; dietary intake ; exposure ; heterocyclic aromatic amines ; women

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