engleski

A new toothpaste effectivnes at reducing gingival inflammation and preventing gingival bleeding: a double blind randomized controlled clinical trial.

Objective: A combined effect of a new toothpaste containing active ingredients potassium nitrate (5, 00%) and zinc citrate (0, 50%) was tested among a randomly selected group of 80 participants who attended the dental clinic of the School of Dental Medicine in Zagreb (Croatia). Materials and Methods: Participants were aged 16-55 years and equally divided by genders. Inclusion criteria were: hypersensitivity to thermal, chemical and mechanical stimulations due to accumulated plaque and gingival retraction. The toothpaste had previously been clinically tested and had been producedaccording to ISO 9001/14001 integrated quality normatives. Soft toothbrushes were used and provided by the same supplier.Plaque index (Aproximal Silness & Löe Index) and gingival bleeding (Probing Bleeding Index after Saxer & Muhlemann) were clinically evaluated at the initial visit and again at 2 and 4week check-up intervals. Data was analyzed by using analysis of variance (ANOVA), t-test and the Mann-Whitney U test. new toothpaste on reducing gingival bledding and inflammation due to accumulated plaqueand can be recommended in preventing periodontal diseases. Plaque index significantly decreased among participants who used the toothpaste with active ingredients potassium nitrate andzinc citrate (15.4%) vs. participants who used the toothpaste without active ingredients (5.8%). Gingival bleeding significantly reduced among participants who used the toothpaste with active ingredients potassium nitrate and zinc citrate (10.9 %) vs. participants who used the toothpaste without active ingredients (2.5%) .

active ingredients ; toothpaste ; hypersensitivity

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