engleski

Occlusal changes associated with 1-year mandibular advancement device treatment of obstructive sleep apnea patients

BACKGROUND: In recent years, the clinical use of mandibular advancement device (MAD) for the treatment of obstructive sleep apnea (OSA) patients has remarkably increased. Although well tolerated, MAD may cause certain side effects. The aim of this study was to investigate potential adverse effects of the custom-made adjustable MAD on occlusal changes after 1 year of treatment. METHODS: A total of 15 patients with mild to moderate OSA were treated with custom-made adjustable MAD (Silensor-sl, Erkodent, Pfalzgrafenweiler, Germany) and they were followed-up after 1 year of treatment. Sleep studies were performed at baseline without the MAD and after 1 year of treatment with the MAD in situ. Lateral cephalometric radiographs were taken for each patient using standardized techniques at baseline and after 1 year of MAD treatment and standard cephalometric analyses were performed using AudaxCeph software (Audax, Ljubljana, Slovenia). RESULTS: The mean apnea-hypopnea index (AHI) decreased significantly from 22.9±5.9 at baseline to 9.7±4.5 episode/h after 1 year of treatment (P<0.001). Overjet decreased from 3.4±0.8 to 3.2±1.2 mm (P=0.903) while overbite changed from 1.9±2.0 to 1.6±1.8 mm (P=0.463) after 1 year of MAD treatment. Lower incisor inclination (21.2±5.0° to 20.0±5.6°, P=0.068) and upper incisor inclination (15.7±6.7° to 15.7±7.2°, P=0.715) did not change significantly throughout the treatment period. CONCLUSIONS: This study demonstrated there were no significant changes in occlusion following 1 year of MAD treatment based on cephalometric analysis.

obstructive sleep apnea ; mandibular advancement device treatment ; occlusal changes

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