engleski

Selective syntheses of A2B-type meso-triarylcorroles

A two-step synthesis of sterically encumbered triarylcorroles by acid-catalyzed [2+1] condensation of dipyrromethanes and aromatic aldehydes followed by oxidation with p-chloranil (or DDQ) is described. Careful monitoring of temperature, solvent, acidic catalyst and reaction time ultimately gave a reliable yield of 15-20% of the corroles, which is a significant improvement as compared to the procedures published earlier. The triarylcorroles prepared are intended for use (I) as sensor elements for anions and neutral molecules in membranes of self-assembled monolayers and (II) as labels for indoles thus providing novel probes for indole-binding proteins.

corrole; triarylcorrole; organic synthesis

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