engleski

The impact of extraction methods on the isolation of pharmacologically active compounds from Vitex agnus-castus - a review

Importance of pharmacologically active natural compounds from plant sources has been re- evaluated in recent years and it has become one of the most active research fields. Despite great advances in medicine, plants still play important roles in healthcare due to their useful natural components such as antioxidants. The main purpose of this review was to present updated information about chemical composition of Vitex agnus-castus (VAC) and its role in healthcare. According to several studies, chemical composition of VAC is characterized by presence of different secondary metabolites, among which iridoids, flavonoids, diterpenoids, essential oils (EO) and ketosteroids are dominant. Differences in chemical composition are observed as a result of different geographic origin and applied extraction method. In this review, the chemical composition of EO and VAC extracts obtained by different extraction methods, including conventional and non-conventional methods, are given and discussed.

Vitex agnus-castus ; extraction ; SC-CO2 ; chemical composition

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