engleski

Chicken Anemia Virus and Infectious Bursal Disease Virus Interfere with Transcription of Chicken IFN-alpha and IFN-gamma mRNA

Chicken anemia virus (CAV) and infectious bursal disease virus (IBDV) are the two most important viruses that cause immunosuppression in commercial chickens. Because inapparent, subclinical infections by these viruses cause immunosuppression, there is need for assesment of the immune status of chickens. Interference with induction of transcription for chicken interferon-alpha (ChIFN-alpha) and ChIFN-gamma was noted after subclinical infections with either CAV or IBDV. Because the immunosuppressive viruses of chickens may interfere with transcription for ChIFN-alpha and ChIFN-gamma , we propose using this interference to asses the immune status of chickens

CAV; IBDV; ChIFN-alpha; ChIFN-gamma

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