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Pregled bibliografske jedinice broj: 820869

K2-EDTA and K3-EDTA Greiner Tubes for HbA1c Measurement


Vrtarić, Alen; Filipi, Petra; Hemar, Marina; Nikolac, Nora; Šimundić, Ana-Maria
K2-EDTA and K3-EDTA Greiner Tubes for HbA1c Measurement // Laboratory medicine, 47 (2016), 1; 39-42 doi:10.1093/labmed/lmv016 (međunarodna recenzija, članak, znanstveni)


Naslov
K2-EDTA and K3-EDTA Greiner Tubes for HbA1c Measurement

Autori
Vrtarić, Alen ; Filipi, Petra ; Hemar, Marina ; Nikolac, Nora ; Šimundić, Ana-Maria

Izvornik
Laboratory medicine (0007-5027) 47 (2016), 1; 39-42

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
HbA1c ; diabetes melitus ; preanalitical phase ; anticoagulant

Sažetak
OBJECTIVE: To determine whether K2- ethylenediaminetetraacetic acid (EDTA) and K3- EDTA Greiner tubes could be used interchangeably for glycosylated hemoglobin, type A1C (HbA1c) measurement via the Abbott Laboratories ARCHITECT chemiluminescent microparticle HbA1c assay on the ARCHITECT i2000SR immunoanalyzer at our university hospital. MATERIALS: We drew blood from a total of 45 outpatients into plastic Greiner Vacuette tubes, some of which were lined with K2-EDTA and others with K3-EDTA anticoagulant. Data are presented as median and interquartile range values. We used the Wilcoxon test and Passing-Bablok regression for tube comparison. RESULTS: For K2-EDTA tubes median HbA1c concentration was 54 mmol/mol (41 to 71 mmol/mol) and for K3- EDTA tubes 56 mmol/mol (43 to 69 mmol/mol). There was no statistically significant difference between K2-EDTA and K3-EDTA (bias= -1.29 mmol/mol ; P = 0.24). Passing-Bablok regression showed that there is no constant and proportional error: y = -0.23 (95% CI[-3.52 to 0.69]) + 1.00( 95% CI[0.98 to 1.06]) x. CONCLUSION: In this study, we provide evidence for the lack of any clinically and statistically significant bias between K2-EDTA and K3-EDTA HbA1c measurements. Thus, Greiner tubes lined with K2-EDTA and those lined with K3-EDTA can safely be used interchangeably to measure HbA1c via the Abbott Laboratories ARCHITECT assay.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Ustanove
KBC "Sestre Milosrdnice"

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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