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Pregled bibliografske jedinice broj: 818302

Patogeneza nediferenciranih spondiloartritisa


Lamot, Lovro; Vidović, Mandica; Perica, Marija; Bukovac Tambić, Lana; Harjaček, Miroslav
Patogeneza nediferenciranih spondiloartritisa // Reumatizam, 62 (2015), 1; 20-26 (podatak o recenziji nije dostupan, pregledni rad, stručni)


CROSBI ID: 818302 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Patogeneza nediferenciranih spondiloartritisa
(Pathogenesis of undifferentiated spondyloarthritis)

Autori
Lamot, Lovro ; Vidović, Mandica ; Perica, Marija ; Bukovac Tambić, Lana ; Harjaček, Miroslav

Izvornik
Reumatizam (0374-1338) 62 (2015), 1; 20-26

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, stručni

Ključne riječi
Spondiloartritis; jSpA; SpA
(Spondyloarthritis; jSpA; SpA)

Sažetak
Spondyloarthritis or spondyloarthropathy (SpA) is a multifactorial disease in which a disturbed interplay occurs between the immune system and environmental factors on a predisposing genetic background, which leads to inflammation and structural damage of target tissue. Many recent researches on development of SpA showed important role of innate and adaptive immunity as well as of prominent bone tissue remodeling which leads to osteoproliferation and ankylosis. It is believed that possible sites of inflammation in SpA are entheses, sinovium and gut. Current knowledge on inflammation and tissue destruction leads to conclusion that SpA is disease characterized by disorders on different levels. Disorder on the first level is disturbed pathogen recognition and immune response activation, on second level disturbed inflammatory cells migration and on third level disturbed immune response regulation. As follows, disease progress depends on range of disturbances: disease course can be short, as in reactive arthritis, or long-lasting with substantial structural damage, as in ankylosing spondylitis. Unfortunately, there are still no confident markers of disease progression, so at the mere beginning disease is often described as undifferentiated.

Izvorni jezik
Hrvatski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekt / tema
108-1083107-0351 - Uloga biomarkera u patofiziologiji seronegativnih spondiloartropatija (Harjaček, Miroslav, MZOS - )

Ustanove
Medicinski fakultet, Zagreb,
KBC "Sestre Milosrdnice"

Profili:

Avatar Url Miroslav Harjaček (autor)

Avatar Url Lovro Lamot (autor)

Avatar Url Lana Bukovac (autor)

Citiraj ovu publikaciju

Lamot, Lovro; Vidović, Mandica; Perica, Marija; Bukovac Tambić, Lana; Harjaček, Miroslav
Patogeneza nediferenciranih spondiloartritisa // Reumatizam, 62 (2015), 1; 20-26 (podatak o recenziji nije dostupan, pregledni rad, stručni)
Lamot, L., Vidović, M., Perica, M., Bukovac Tambić, L. & Harjaček, M. (2015) Patogeneza nediferenciranih spondiloartritisa. Reumatizam, 62 (1), 20-26.
@article{article, year = {2015}, pages = {20-26}, keywords = {Spondyloarthritis, jSpA, SpA}, journal = {Reumatizam}, volume = {62}, number = {1}, issn = {0374-1338}, title = {Pathogenesis of undifferentiated spondyloarthritis}, keyword = {Spondyloarthritis, jSpA, SpA} }

Časopis indeksira:


  • Scopus
  • MEDLINE





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