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Pregled bibliografske jedinice broj: 816826

The Effect of Body Position on Intraocular and Intracranial Pressure in Rabbits


Klarica, Marijan; Kuzman, Tomislav; Jurjević, Ivana; Radoš, Milan; Tvrdeić, Ante; Orešković, Darko
The Effect of Body Position on Intraocular and Intracranial Pressure in Rabbits // Acta Neurochirurgica. Supplementum, 122 (2016), 279-282 doi:10.1007/978-3-319-22533-3_55 (podatak o recenziji nije dostupan, članak, ostalo)


Naslov
The Effect of Body Position on Intraocular and Intracranial Pressure in Rabbits

Autori
Klarica, Marijan ; Kuzman, Tomislav ; Jurjević, Ivana ; Radoš, Milan ; Tvrdeić, Ante ; Orešković, Darko

Izvornik
Acta Neurochirurgica. Supplementum (0065-1419) 122 (2016); 279-282

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, ostalo

Ključne riječi
Body position ; Cerebrospinal fluid hydrodynamics ; Cerebrospinal fluid pressure ; Intraocular pressure

Sažetak
BACKGROUND: The correlation between cerebrospinal fluid (CSF) and intraocular pressure (IOP) is still unclear. We compared CSF and IOP measured by the same invasive technique using a new experimental model in rabbits during changes of body position. METHODS: Pressure changes were recorded in the lateral ventricle (LV), the cortical subarachnoid space (CSS), and the anterior ocular chamber of anesthetized rabbits (n = 12). Animals and measuring instruments were both fixed on a board at an adequate hydrostatic level. RESULTS: In a horizontal position, control IOP (15.1 ± 1.6 cmH2O) and CSF pressure in the LV (12.4 ± 0.6 cmH2O) and CSS (12.2 ± 0.9 cmH2O) were similar during the 60-min period. When changing the body position from horizontal to vertical (upright), CSF pressures decreased drastically (LV = -5.5 ± 2.6 cmH2O and CSS = -7.7 ± 2.3 cmH2O), while the IOP decreased moderately (IOP = 13.3 ± 0.5 cmH2O). CONCLUSION: Change in body position from horizontal to vertical causes drastic changes in CSF pressure and moderate changes in IOP. Thus, IOP is not reflected by the CSF pressure. In an upright position, the values of CSF pressure were equal to the hydrostatic distance between measuring points and the foramen magnum, which suggests that CSF pressure inside the cranium depends on its anatomical and biophysical features, and not on CSF secretion and absorption.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti



POVEZANOST RADA


Projekt / tema
098-1080231-2328 - Hidrodinamika cerebrospinalnog fluida (Darko Orešković, )
108-1080231-0023 - Patofiziologija cerebrospinalnog likvora i intrakranijskog tlaka (Marijan Klarica, )

Ustanove
Institut "Ruđer Bošković", Zagreb,
Medicinski fakultet, Zagreb

Časopis indeksira:


  • Scopus
  • MEDLINE


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