engleski

Cortical Maturation In Mouse Brain: Layer By Layer

Several neurological and psychiatric diseases alter the process of layer formation during maturation, leading to changes in cortical morphology, like lissencephaly. Neurodevelopmental studies of cortical morphology could help identifying abnormalities in cortical lamination both in preclinical and clinical research. Here, we employed two different MR techniques in order to visualize microscopic as well as morphometric changes of the mouse cortex and to monitor the development of cortical layers non-invasively.

MRI; mouse; brain; development

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