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Gender differences in depression (CROSBI ID 228385)

Prilog u časopisu | stručni rad

Šagud, Marina ; Hotujac, Ljubomir, Mihaljević-Peleš, Alma ; Jakovljević, Miro Gender differences in depression // Collegium antropologicum, 26 (2002), 1; 149-157

Podaci o odgovornosti

Šagud, Marina ; Hotujac, Ljubomir, Mihaljević-Peleš, Alma ; Jakovljević, Miro

engleski

Gender differences in depression

Abstract Depression is twice as common in women as in men, although some concern has been raised in terms of misdiagnosing depression in men. The incidence of depression in women varies during the life span. The peak incidence during childbearing years appears to be associated with cyclic hormonal changes. Women also present with reproductive -specific mood disorders: pre-menstrual dysphoric disorder (PMDD), depression in pregnancy, postpartal mood disorder (PDD) and perimenopausal depressive disorder. Gender differences were repeatedly observed in response to antidepressant medication. Premenopausal women appear to respond poorly and to show low tolerability to TCAs, but they tend to show greater responsiveness to the SSRIs. In contrast, men and postmenopausal women can respond equally to the TCAs and SSRIs. These differences are contributed to gender differences in pharmacokinetics of antidepressants and to the influence of menstrual cycle. These findings suggest the need for a gender-specific approach to the evaluation and management of depression.

Major depressive disorder (MDD); women

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Podaci o izdanju

26 (1)

2002.

149-157

objavljeno

0350-6134

Povezanost rada

Kliničke medicinske znanosti

Indeksiranost