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Prevention and Treatment of Ovarian Hyperstimulation Syndrome

Ovarian hyperstimulation syndrome (OHSS) is a clinical symptom complex associated with ovarian enlargement resulting from exogenous gonadotropin therapy. In severe cases, a critical condition develops with massive ascites, marked ovarian enlargement, pleural effusion, electrolyte imbalance, hypovolemia with hypotension, oliguria, hemoconcentration, and thromboembolism (Madill JJ et al., 2008). Moderate to severe ovarian hyperstimulation syndrome (OHSS) has been calculated to occur in 0.2% to 2% of all ovarian stimulation cycles (Binder H et al., 2007). Severe OHSS can be a life-threatening complication. The prognosis is usually worse in patients who get pregnant and have this syndrome.

OHSS, IVF, ART, ovarian stimulation

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