Therapeutic implication of molecular profiling in patients with non – small cell lung cancer (CROSBI ID 228304)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Jakopović, Marko ; Smojver-Ježek, Silvana ; Chalfe, Nabil ; Redžepi, Gzim ; Janković, Mateja ; Čučević, Branka ; Mihelčić, Dina ; Stančić- Rokotov, Dinko ; Samaržija, Miroslav ;
engleski
Therapeutic implication of molecular profiling in patients with non – small cell lung cancer
Traditional, 'one size fits all' approach to chemotherapy has reached efficacy plateau. The development of molecular biomarkers is crucial for improving efficacy of therapy in patients with NSCLC.We review prognostic and predictive value of molecular biomarkers with special overview on biomarker-driven personalized therapy of NSCLC. Main focus is this review is on significance of EGFR mutations and ALK – EML4 alterations on due to availability of targeted drugs against these specific aberrations.
molecular biomarkers; non-small cell lung cancer
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Podaci o izdanju
Povezanost rada
Kliničke medicinske znanosti
