Napredna pretraga

Pregled bibliografske jedinice broj: 815718

Efficacy and safety of budesonide/formeterol combination therapy in asthma patients


Jakopović, Marko; Pavičić, Fadila; Redžepi, Gzim; Pleština, Sanja; Janković, Mateja; Franić, Zrinka; Šamija, Mirko; Samaržija, Miroslav
Efficacy and safety of budesonide/formeterol combination therapy in asthma patients // Collegium antropologicum, 33 (2009), 2; 587-591 (međunarodna recenzija, članak, znanstveni)


Naslov
Efficacy and safety of budesonide/formeterol combination therapy in asthma patients

Autori
Jakopović, Marko ; Pavičić, Fadila ; Redžepi, Gzim ; Pleština, Sanja ; Janković, Mateja ; Franić, Zrinka ; Šamija, Mirko ; Samaržija, Miroslav

Izvornik
Collegium antropologicum (0350-6134) 33 (2009), 2; 587-591

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
asthma ; asthma control ; budenoside/formoterol

Sažetak
Budesonide/formoterol as single inhaler was developed for treating asthma patients who are not adequately controlled on glucocorticoides alone. The aim of this study was to evaluate efficacy, safety and patient/physician satisfaction of budesonide/formoterol therapy.Total of 268 asthma patients (120 men, mean age 38.8 +/- 37.2 years, and 148 women, mean age 42.2 +/- 32 years) were included in the study. All patients received budesonide/formoterol bid (640 mcg of budesonide and 18 mcg of formoterol daily) during run-in period for three weeks. Patients were followed during 14 weeks at 5 visits. At each visit lung function (FEV1 and PEF) was measured, presence of side affects was recorded and questionnaire was given to patients and physicians to estimate the level of satisfaction with budesonide/formoterol therapy (1 very unsatisfied to 5 very satisfied). Significant improvement was noticed in FEV1, from 76.25% of predicted value to 86.94% (p < 0.01) ; and in PEF from 380.84 L/min to 442.29 L/min (p < 0.01) in all patients. At the end of the study patients' satisfaction with budesonide/formeterol therapy was significantly improved comparing with satisfaction with previously taken therapy, in average grade, from 2.94 to 4.56 (p < 0.01), and similar results were noticed with physicians' satisfaction, from 2.60 to 4.41 (p < 0.01). Budesonide/formoterol in single inhaler, significantly improved lung function in patients with asthma

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Ustanove
Medicinski fakultet, Zagreb,
KBC "Sestre Milosrdnice",
Klinički bolnički centar Zagreb

Citiraj ovu publikaciju

Jakopović, Marko; Pavičić, Fadila; Redžepi, Gzim; Pleština, Sanja; Janković, Mateja; Franić, Zrinka; Šamija, Mirko; Samaržija, Miroslav
Efficacy and safety of budesonide/formeterol combination therapy in asthma patients // Collegium antropologicum, 33 (2009), 2; 587-591 (međunarodna recenzija, članak, znanstveni)
Jakopović, M., Pavičić, F., Redžepi, G., Pleština, S., Janković, M., Franić, Z., Šamija, M. & Samaržija, M. (2009) Efficacy and safety of budesonide/formeterol combination therapy in asthma patients. Collegium antropologicum, 33 (2), 587-591.
@article{article, year = {2009}, pages = {587-591}, keywords = {asthma, asthma control, budenoside/formoterol}, journal = {Collegium antropologicum}, volume = {33}, number = {2}, issn = {0350-6134}, title = {Efficacy and safety of budesonide/formeterol combination therapy in asthma patients}, keyword = {asthma, asthma control, budenoside/formoterol} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Social Science Citation Index (SSCI)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE