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Microscopic Insight into the Human Consciousness


Šoša, Ivan; Stemberga, Valter; Strenja-Linic, Ines; Baniček Šoša, Ivanka; Cuculić, Dražen
Microscopic Insight into the Human Consciousness // book of abstracts 19th annual meeting of the association for the scientific study of consciousness
Pariz, Francuska, 2015. (poster, međunarodna recenzija, sažetak, znanstveni)


Naslov
Microscopic Insight into the Human Consciousness

Autori
Šoša, Ivan ; Stemberga, Valter ; Strenja-Linic, Ines ; Baniček Šoša, Ivanka ; Cuculić, Dražen

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Book of abstracts 19th annual meeting of the association for the scientific study of consciousness / - , 2015

Skup
19th annual meeting of the association for the scientific study of consciousness

Mjesto i datum
Pariz, Francuska, 07.-10. 07.2015

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Claustrum; death

Sažetak
BACKGROUND: Recent reports delivered consciousness into a materialistic realm and it has become quite tangible and attainable in form of a small, unilateral area1 with a prospect of using functional neuroimaging developments and deep-brain stimulation. Stimulation, including different pathological processes (diffuse hemispheric damage, brain-stem damage or bilateral thalamic damage) disruptes consciousness.Changes in the claustrum would be microscopically visible on post-mortem neurons similar to the changes described in paper of Pulsinelli and Brierley. HYPOTHESIS: - microscopically assessing claustrum/insula complexes of 15 deceased “minimally conscious” patients. Ability of claustral projection neurons that express the gene encoding the vesicular glutamate transporter (Vglut) 2 should help us identify the claustrum. Neuronal cell death will be assessed at 200× magnification, according to 0-3 scale by estimating the percentage of acidophilic neurons. Control group should comprise of 15 counterparts, deceased as traumatic brain injury (TBI) victims presented with: diffuse hemispheric damage (N=7), brain-stem damage or bilateral thalamic damage (N=8). PURPOSE: Highlighting the detachment of modern consciousness concept from the established criteria of declaring death, demonstrating benefits of simple microscopic examination.

Izvorni jezik
Engleski