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Pregled bibliografske jedinice broj: 814698

Pulled Polymer Loops as a Model for the Alignment of Meiotic Chromosomes


Lin, Yen Ting; Frömberg, Daniela; Huang, Wenwen; Delivani, Petrina; Chacón, Mariola; Tolić, Iva M.; Jülicher, Frank; Zaburdaev, Vasily
Pulled Polymer Loops as a Model for the Alignment of Meiotic Chromosomes // Physical Review Letters, 115 (2015), 208102-1 doi:10.1103/PhysRevLett.115.208102 (međunarodna recenzija, članak, znanstveni)


Naslov
Pulled Polymer Loops as a Model for the Alignment of Meiotic Chromosomes

Autori
Lin, Yen Ting ; Frömberg, Daniela ; Huang, Wenwen ; Delivani, Petrina ; Chacón, Mariola ; Tolić, Iva M. ; Jülicher, Frank ; Zaburdaev, Vasily

Izvornik
Physical Review Letters (0031-9007) 115 (2015); 208102-1

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
DNA recombination ; chromosome folding

Sažetak
During recombination, the DNA of parents exchange their genetic information to give rise to a genetically unique offspring. For recombination to occur, homologous chromosomes need to find each other and align with high precision. Fission yeast solves this problem by folding chromosomes in loops and pulling them through the viscous nucleoplasm. We propose a theory of pulled polymer loops to quantify the effect of drag forces on the alignment of chromosomes. We introduce an external force field to the concept of a Brownian bridge and thus solve for the statistics of loop configurations in space.

Izvorni jezik
Engleski

Znanstvena područja
Fizika, Biologija



POVEZANOST RADA


Ustanove
Institut "Ruđer Bošković", Zagreb

Autor s matičnim brojem:
Iva Marija Tolić, (260543)

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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