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The Benefit and Future of Pharmacogenetics (CROSBI ID 56138)

Prilog u knjizi | izvorni znanstveni rad

Samardžić, Janko ; Švob Štrac, Dubravka ; van den Anker, Johannes N. The Benefit and Future of Pharmacogenetics // Total Intravenous Anesthesia and Target Controlled Infusions. A Comprehensive Global Anthology / Absalom, Anthony R. ; Mason, Keira P. (ur.).: Springer, 2017. str. 697-711 doi: 10.1007/978-3-319-47609-4_38

Podaci o odgovornosti

Samardžić, Janko ; Švob Štrac, Dubravka ; van den Anker, Johannes N.

engleski

The Benefit and Future of Pharmacogenetics

In recent years pharmacogenetics has received major attention in many areas of medicine, giving the potential basis of precision medicine in the near future. Determination of genetic factors of prognostic value for a target drug choice and dosing regimen will improve the safe and effective use of medicines in patients of all ages. Individual differences in pharmacological responses might lead to serious clinical problems such as difficulties in reaching optimal efficacy, appearance of drug interactions and adverse drug reactions (ADRs). Based upon the current knowledge, it is clear that an early adjustment of a therapy regimen using genetic characteristics of a patient can help prevent some of these side effects. Thus, the application of pharmacogenetics might have a great potential in helping providers to reduce and prevent ADRs and to improve therapeutic drug efficacy .

pharmacogenetics ; total intravenous anesthesia ; therapeutic drug efficacy ; adverse drug reactions

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Podaci o prilogu

697-711.

objavljeno

10.1007/978-3-319-47609-4_38

Podaci o knjizi

Total Intravenous Anesthesia and Target Controlled Infusions. A Comprehensive Global Anthology

Absalom, Anthony R. ; Mason, Keira P.

Springer

2017.

978-3-319-47607-0

Povezanost rada

Temeljne medicinske znanosti

Poveznice