Cardiac manifestations in alcoholic liver disease (CROSBI ID 227415)
Prilog u časopisu | pregledni rad (znanstveni) | međunarodna recenzija
Podaci o odgovornosti
Milić, Sandra ; Lulić, Davorka ; Štimac, Davor ; Ružić, Alen ; Zaputović, Luka
engleski
Cardiac manifestations in alcoholic liver disease
Alcoholic liver disease is the most prevalent cause of progressive liver disease in Europe. Alcoholic cirrhosis occurs in 8%-20% of cases of alcoholic liver disease. It has significant influence on cardiovascular system and haemodynamics through increased heart rate, cardiac output, decreased systemic vascular resistance, arterial pressure and plasma volume expansion. Cirrhotic cardiomyopathy is characterised by systolic and diastolic dysfunction and electrophysiological abnormalities, if no other underlying cardiac disease is present. It is often unmasked only during pharmacological or physiological stress, when compensatory mechanisms of the heart become insufficient to maintain adequate cardiac output. Low-to-moderate intake of alcohol can be cardioprotective. However, heavy drinking is associated with an increased risk of cardiovascular diseases, such as alcoholic cardiomyopathy, arterial hypertension, atrial arrhythmias as well as haemorrhagic and ischaemic stroke. Alcoholic cardiomyopathy is characterised by dilated left ventricle (LV), increased LV mass, normal or reduced LV wall thickness and systolic dysfunction.
Alcoholic cardiomyopathy ; Alcoholic liver cirrhosis ; Alcoholic liver disease ; Cirrhotic cardiomyopathy ; Hemodynamics
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Podaci o izdanju
98 (1086)
2016.
235-239
objavljeno
0032-5473
10.1136/postgradmedj-2015-133755
Povezanost rada
Kliničke medicinske znanosti