engleski

Hypersensitivity Reactions to Iodinated Contrast Media

Iodinated contrast agents are used to enhance X- ray procedures and can cause both immediate and non-immediate hypersensitivity reactions. Due to their increased use, related hypersensitivity reactions are also on the rise. Following the introduction of nonionic, low-osmolar contrast media the number of hypersensitivity reactions has decreased, but possible severe reactions, such as anaphylaxis, still represent a major concern. Radiologists and cardiologists should keep in mind that previously non-exposed patients could already be sensitized, and could present with a hypersensitivity reaction following the first administration. In previous reactors, especially in cases of severe reactions, an allergy work-up could provide useful information regarding contrast media selection. In patients with a confirmed allergy to contrast media, a contrast medium that has a negative skin testshould be chosen, with additional premedication. However, we must keep in mind that none of these measures offer a complete protection from repeated reaction.

adverse reaction ; iodinated contrast media ; premedication

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