engleski

Influence of the metabolic syndrome definitions on electrocardiographic abnormalities

Aims: Investigating the influence of metabolic syndrome (MetS) definitions on electrocardiographic (ECG) abnormalities appearance. Materials and methods: A retrospective study on 2400 patients who underwent ECG, between June 2013 and July 2014, at Center for Internal Medicine and Dialysis was performed. MetS was diagnosed by the revised National Cholesterol Education Program - Adult Treatment Panel III (NCEP-ATP III) and IDF (International Diabetes Federation) criteria. Patients were selected into two groups (with/without MetS) and analysed by baseline (medical, demographic and anthropometric data) and ECG data (Minnesota codes). Results: There were 1038 (43.3%) and 1276 (53.2%) patients with NCEP-ATP III and IDF MetS, respectively. They had higher rates of total ischemic, non-ischemic, major and minor ECG abnormalities, 2nd degree atrioventricular (AV) block, frequent extrasy- stoles, left axis deviation, high voltage QRS, T wave flattening, low voltage QRS and resting heart rate (HR) ≥95 bpm (p<0.05). Additionally, patients with NCEP-ATP III MetS had higher rates of T wave inversion, right bundle branch block and lower rates of resting HR 80-94 bpm, while those with IDF MetS had higher rates of 3rd degree AV block (p<0.05). There were significant differen- ces between two MetS definitions in appearance of the most ECG changes (p<0.05), except of right axis deviation (p=0.480). Conclusion: Two investigated MetS definitions have significant differences in appearance of the most ECG abnormalities.

metabolic cardiovascular syndrome; abdominal obesity; ECG; Ischemic heart disease; atherogenesis

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