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Pregled bibliografske jedinice broj: 802623

In vitro investigation of the antimicrobial activity of a series of lipophilic phenols and naphthols


Govender, Thavendran; Govinden, Usha; Mocktar, Chunderik; Kruger, Hendrik G.; Veljković, Jelena; Cindro, Nikola; Bobinac, Damir; Žabčić, Ivana; Mlinarić-Majerski, Kata; Basarić, Nikola
In vitro investigation of the antimicrobial activity of a series of lipophilic phenols and naphthols // South african journal of chemistry-suid-afrikaanse tydskrif vir chemie, 69 (2016), 44-50 doi:10.17159/0379-4350/2016/v69a6 (međunarodna recenzija, članak, znanstveni)


Naslov
In vitro investigation of the antimicrobial activity of a series of lipophilic phenols and naphthols

Autori
Govender, Thavendran ; Govinden, Usha ; Mocktar, Chunderik ; Kruger, Hendrik G. ; Veljković, Jelena ; Cindro, Nikola ; Bobinac, Damir ; Žabčić, Ivana ; Mlinarić-Majerski, Kata ; Basarić, Nikola

Izvornik
South african journal of chemistry-suid-afrikaanse tydskrif vir chemie (0379-4350) 69 (2016); 44-50

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Antimicrobial activity ; phenols ; naphthols ; quinone methides.

Sažetak
Five groups of phenols/naphthols (42 compounds in total) were synthesized and screened against Gram-positive Staphylococcus aureus and Bacillus subtilis, Gram-negative Escherichia coli and Klebsiella pneumoniae, and the fungus Candida albicans. Whereas compounds were found inactive against Gram-negative bacteria, potent activities against Gram-positive bacteria were observed. The activities correlate with the ability of molecules to form quinone methides, suggesting potential new modes of action.

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA


Projekt / tema
0098-0982933-2911
HRZZ-IP-2014-09-6312 - Supramolekulska kontrola fotokemijskih reakcija eliminacije (Nikola Basarić, )
HRZZ-UIP-02.05/25 - Fotokemija policikličkih molekula: od istraživanja mehanizma reakcije do novih lijekova i medicinskih primjena (Nikola Basarić, )

Ustanove
Institut "Ruđer Bošković", Zagreb

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus


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