engleski

Prediction of the Y Chromosome Haplogroups within a Recently Settled Turkish Population in Sarajevo, Bosnia and Herzegovina

Analysis of Y-Chromosome haplogroup distribution is widely used in investigation of geographical clustering of different populations. Hence, they play an important role in population genetics, human migration patterns and even in forensic investigations. Individual determination of these haplogroups is mostly based on the analysis of the SNP markers located in non-recombining part of Y chromosome. On the other hand, the number of forensics and anthropology studies investigating short tandem repeats on the Y-chromosome (Y-STRs) increases rapidly every year. These markers have been used as successful haplogroup prediction methods in the last few years. Therefore, we incorporated this method into our studies. Previously obtained Y-STR haplotypes (23 loci) from 100 unrelated Turkish males recently settled in Sarajevo were used for the determination of haplogroups via ‘Whit Athey’s Haplogroup Predictor’ software. The Bayesian probability of 90 of the studied haplotypes is greater than 92.2% and ranges from 51.4% to 84.3% for the remaining 10 haplotypes. A distribution of 17 different haplogroups was found ; Y- haplogroup J2a is the most prevalent, having been found in 26% of all the samples, whereas R1b, G2a and R1a were less prevalent, covering a range of 10% to 15% of all the samples. Together, these four haplogroups account for 63% of all Y-chromosomes. The distribution of Y-chromosome haplogroups is significantly consistent with previously published data for the Turkish population residing in Turkey, which is why the analyzed population could be recognized as a representative sample for that population.

Y-Chromosome; haplogroup predictor; clustering; Y-STRs; Turkish population

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