Explorations of mechanochemical Friedel-Crafts acylations (CROSBI ID 631140)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Đud, Mateja ; Štrukil, Vjekoslav ; Margetić, Davor
engleski
Explorations of mechanochemical Friedel-Crafts acylations
Friedel-Crafts acylation reactions were exploited in the preparation of ketone functionalized aromatics (Scheme 1). For this purpose, solvent-free mechanochemical reaction conditions of this industrially important reaction were developed [1]. Reaction parameters such as FC catalyst, time, ratio of reagents, milling support, frequency of milling, size and number of milling balls, solvents for liquid assisted grinding were studied to establish the optimal reaction conditions [2]. To explore the scope of the reaction, different aromatic hydrocarbons were used in conjuction with anhydrides and acyl halides. It was shown that certain FC reactive aromatics could be effectively functionalized by FC acylations carried out in ball-milling conditions without the presence of solvent.
Friedel-Crafts acylation ; mechanochemistry ; mechanism
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Podaci o prilogu
2015.
objavljeno
Podaci o matičnoj publikaciji
Podaci o skupu
PACIFICHEM 2015 International Chemical Congress of Pacific Basin Societies
pozvano predavanje
15.12.2015-20.12.2015
Honolulu (HI), Sjedinjene Američke Države