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Pregled bibliografske jedinice broj: 788766

Dietary effect on c-peptide preservation in type 1 diabetic pregnant women


Đelmiš, Josip; Radončić, Erden; Horvatiček, Marina; Ivanišević, Marina.
Dietary effect on c-peptide preservation in type 1 diabetic pregnant women // Gynaecologia et perinatologia : journal for gynaecology, perinatology, reproductive medicine and ultrasonic diagnostics, 24 (2015), 1; 31-36 (međunarodna recenzija, pregledni rad, znanstveni)


Naslov
Dietary effect on c-peptide preservation in type 1 diabetic pregnant women

Autori
Đelmiš, Josip ; Radončić, Erden ; Horvatiček, Marina ; Ivanišević, Marina.

Izvornik
Gynaecologia et perinatologia : journal for gynaecology, perinatology, reproductive medicine and ultrasonic diagnostics (1330-0091) 24 (2015), 1; 31-36

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
pregnancy; type 1 diabetes mellitus; C-peptide; nicotinamide; omega-3 fatty acids; vitamins D and E

Sažetak
Insulin is the main hormone in the regulation of glucose metabolism. Insulin is synthesized in the Langerhans islet β-cells as the proinsulin precursor, from which C-peptide and insulin are formed by proteolytic cleavage. In patients with type 1 diabetes mellitus (DM-1), complex interplay of genetic, exogenous ad autonomic factors leads to selective destruction of pancreatic β-cells, thus compromising insulin synthesis and secretion. Patients with DM-1 can produce exogenous insulin to a certain extent, however, insulin secretion undergoes gradual reduction due to selective destruction of β-cell function. Both C-peptide and insulin are secreted to portal circulation in equimolar amounts. There is an association of elevated C-peptide concentration with great reduction of hypoglycemic episodes, HbA1c values and microvascular complications. Studies have demonstrated that vitamins D and E, nicotinamide and polyunsaturated fatty acids (omega-3 fatty acids) may have protective effects in DM-1. Our investigations showed C-peptide to increase in both healthy and DM-1 pregnant women. This review article describes the impact of pregnancy and diet on β-cell function in women with DM-1.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti



POVEZANOST RADA


Projekt / tema
108-1080401-0385 - Dijabetes i metabolički sindrom nakon prethodnog gestacijskog dijabetesa (Marina Ivanišević, )
108-1080401-0386 - Metaboličke i endokrine promjene u dijabetičnih trudnica (Josip Đelmiš, )

Ustanove
Medicinski fakultet, Zagreb

Citiraj ovu publikaciju

Đelmiš, Josip; Radončić, Erden; Horvatiček, Marina; Ivanišević, Marina.
Dietary effect on c-peptide preservation in type 1 diabetic pregnant women // Gynaecologia et perinatologia : journal for gynaecology, perinatology, reproductive medicine and ultrasonic diagnostics, 24 (2015), 1; 31-36 (međunarodna recenzija, pregledni rad, znanstveni)
Đelmiš, J., Radončić, E., Horvatiček, M. & Ivanišević, M. (2015) Dietary effect on c-peptide preservation in type 1 diabetic pregnant women. Gynaecologia et perinatologia : journal for gynaecology, perinatology, reproductive medicine and ultrasonic diagnostics, 24 (1), 31-36.
@article{article, year = {2015}, pages = {31-36}, keywords = {pregnancy, type 1 diabetes mellitus, C-peptide, nicotinamide, omega-3 fatty acids, vitamins D and E}, journal = {Gynaecologia et perinatologia : journal for gynaecology, perinatology, reproductive medicine and ultrasonic diagnostics}, volume = {24}, number = {1}, issn = {1330-0091}, title = {Dietary effect on c-peptide preservation in type 1 diabetic pregnant women}, keyword = {pregnancy, type 1 diabetes mellitus, C-peptide, nicotinamide, omega-3 fatty acids, vitamins D and E} }

Časopis indeksira:


  • Scopus


Uključenost u ostale bibliografske baze podataka:


  • EMBASE (Excerpta Medica)
  • SCOPUS