engleski

Variety of polymeric materials based on polylactide

Production of synthetic polymers increases steadily, witnessing almost exponential growth since the start of their industrial production. However, biopolymer materials record even larger growth during last 20 years whereat that term encompasses materials obtained from row biomaterials, materials for biological (e.g. medical and pharmaceutical) purposes, in various biological environments (non-)degradable or compostable materials. Among a dozen of the most frequently used biopolymers a special place belongs to polyesters (poly(-caprolactone), polylactide (PLA), polyglycolide (PGA) and their copolymers (PLA-co-PGA), poly (ortho esters)). Application of these biodegradable polymers in numerous medical and biomedical fields is of a particular importance. The great advantage of these materials is ability to adjust their properties by varying the composition and methods of preparing and processing the material. Biopolymers based on PLA isomers and its copolymers with other monomers are used for the preparation of various products such as implants, hydrogels, carriers for delivery of therapeutic or diagnostic agents, substrates for tissue engineering. In this work different PLA based materials were prepared and tested. It is shown how to obtain materials of different properties and behavior, which is confirmed by numerous analyzes: nuclear magnetic resonance (1H NMR), infrared spectroscopy (FTIR), thermogravimetric analysis (TA), differential scanning calorimetry (DSC), scanning electron microscopy (SEM ), testing of mechanical and surface properties.

Polymers; Lactide; Biopolymers

nije evidentirano