engleski

Assessing the validity of an ELISA test for the serological diagnosis of equine viral arteritis

The aim of this study was to evaluate the diagnostic performance of ELISA based on the virus neutralisation (VN) test which is recommended by the World Organization for Animal Health (OIE) as “gold standard” for the detection of the antibodies to equine arteritis virus as well as to evaluate its application as screening test in a routine laboratory diagnostics. The ELISA showed high sensitivity and low specificity and had a moderate agreement with VN-test. Therefore, 13, 56% of positive samples by ELISA were false positive as well as 2, 54% of negative samples by ELISA were thrue positive. The percentage agreement between ELISA and VN-test was 47 % Kappa (CI 95% from 27% to 67%).

evaluation ; diagnostic test ELISA ; equine viral arteritis

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