Pretražite po imenu i prezimenu autora, mentora, urednika, prevoditelja

Napredna pretraga

Pregled bibliografske jedinice broj: 786076

Evaluation and Management of Neonatal Indirect Hyperbilirubinaemia at the University Pediatric Clinic in Skopje, Republic of Macedonia


Papazovska Cherepnalkovski, Anet; Piperkova, Katica; Palčevska, Kočevska; Aluloska, N; Zdraveska, N; Gruev, Todor; Krželj, Vjekoslav
Evaluation and Management of Neonatal Indirect Hyperbilirubinaemia at the University Pediatric Clinic in Skopje, Republic of Macedonia // Medicus, 20 (2015), 2; 221-119 (podatak o recenziji nije dostupan, članak, stručni)


CROSBI ID: 786076 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Evaluation and Management of Neonatal Indirect Hyperbilirubinaemia at the University Pediatric Clinic in Skopje, Republic of Macedonia

Autori
Papazovska Cherepnalkovski, Anet ; Piperkova, Katica ; Palčevska, Kočevska ; Aluloska, N ; Zdraveska, N ; Gruev, Todor ; Krželj, Vjekoslav

Izvornik
Medicus (1409-6366) 20 (2015), 2; 221-119

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, stručni

Ključne riječi
hyperbilirubinemia; neonate; ABO incompatibility; sepsis; prematurity; G6PD defiiency; evaluation and management; Republic of Macedonia

Sažetak
Introduction: Neonatal hyperbilirubinemia, defined as a total serum bilirubin level > 86 μmol/L, is a frequent problem affecting approximately 60% of term and 80% of preterm newborns. Clinical challenge is to differentiate between the majority of physiologically jaundiced infants and those with pathological causes, thus to establish appropriate management plan. Objectives: Purpose of the study was to review evaluation and management of neonatal indirect hyperbilirubinemia at the University Pediatric Clinic Neonatology Department over a two year period. Methods: Medical records of 284 newborns with indirect hyperbilirubinemia were retrospectively analyzed for history data, clinical presentation, diagnostic procedure and the therapy applied. Results: Most prevalent was jaundice of undefined etiology (44.37%), followed by neonatal infection, prematurity, hemolysis, and birth trauma. The mean peak serum bilirubin concentration in the undefined etiology group was 333.4±91.1 μmol/l. The peak bilirubin levels and reticulocites in hemolytic jaundice were significantly higher compared to the other etiologies. The fist control serum bilirubin level was significantly higher in newborns with hemolysis compared to the groups of premature newborns and jaundice of undefined etiology. Analyzed groups significantly differed according to the day bilirubin reached peak. Most cases were treated with phototherapy, and 2.11% with exchange transfusion. Conclusions: Hyperbilirubinemia is a frequent pathology at the University Pediatric Clinic- Skopje, R. Macedonia. Most cases are treated with less severe jaundice of undefined etiology. Immediate awareness and management is required for those 15% of infants with hemolytic causes of jaundice that carry a significant risk for early and severe hyperbilirubinemia.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Ustanove:
KBC Split,
Medicinski fakultet, Split


Citiraj ovu publikaciju

Papazovska Cherepnalkovski, Anet; Piperkova, Katica; Palčevska, Kočevska; Aluloska, N; Zdraveska, N; Gruev, Todor; Krželj, Vjekoslav
Evaluation and Management of Neonatal Indirect Hyperbilirubinaemia at the University Pediatric Clinic in Skopje, Republic of Macedonia // Medicus, 20 (2015), 2; 221-119 (podatak o recenziji nije dostupan, članak, stručni)
Papazovska Cherepnalkovski, A., Piperkova, K., Palčevska, K., Aluloska, N., Zdraveska, N., Gruev, T. & Krželj, V. (2015) Evaluation and Management of Neonatal Indirect Hyperbilirubinaemia at the University Pediatric Clinic in Skopje, Republic of Macedonia. Medicus, 20 (2), 221-119.
@article{article, year = {2015}, pages = {221-119}, keywords = {hyperbilirubinemia, neonate, ABO incompatibility, sepsis, prematurity, G6PD defiiency, evaluation and management, Republic of Macedonia}, journal = {Medicus}, volume = {20}, number = {2}, issn = {1409-6366}, title = {Evaluation and Management of Neonatal Indirect Hyperbilirubinaemia at the University Pediatric Clinic in Skopje, Republic of Macedonia}, keyword = {hyperbilirubinemia, neonate, ABO incompatibility, sepsis, prematurity, G6PD defiiency, evaluation and management, Republic of Macedonia} }
@article{article, year = {2015}, pages = {221-119}, keywords = {hyperbilirubinemia, neonate, ABO incompatibility, sepsis, prematurity, G6PD defiiency, evaluation and management, Republic of Macedonia}, journal = {Medicus}, volume = {20}, number = {2}, issn = {1409-6366}, title = {Evaluation and Management of Neonatal Indirect Hyperbilirubinaemia at the University Pediatric Clinic in Skopje, Republic of Macedonia}, keyword = {hyperbilirubinemia, neonate, ABO incompatibility, sepsis, prematurity, G6PD defiiency, evaluation and management, Republic of Macedonia} }




Contrast
Increase Font
Decrease Font
Dyslexic Font