engleski

The NMR Study of Products Obtained by Photorearrangement of Pyridinium Salts

Light induced molecular changes are important in chemistry, biochemistry and medicine. Namely, photochemical reactions can induce transformation of molecules resulting in completely different chemical behavior and biological activity of the products. Pyridinium salts are present in the structure in NAD+ and NADP+ cofactors, which are essential for functioning of all living cells. Moreover, pyridinium derivatives are photochemicaly reactive, 1, 2 which in principle enables activation or deactivation of biochemical processes involving NAD+ and NADP+ cofactors. Therefore, a deeper understanding of photophysical transformation of pyridinium salts is of great relevance and could redirect future studies in life sciences.3 Herein we present systematic investigations of photochemistry of o-, m- and p-methyl substituted N-metyhlpyridinium salts. NMR spectroscopy was used to reveal complex structures of the rearranged products.

N-metyhlpyridinium salts ; photochemistry ; NMR spectroscopy

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