Chancriform Pyoderma: A Forgotten Disease (CROSBI ID 221908)
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Podaci o odgovornosti
Celić, Dijana ; Lipozenčić, Jasna ; Budimčić, Dragomir ; Radoš, Jaka ; Ljubojević, Ljubojević Jolanda Kanižaj Rajković,
engleski
Chancriform Pyoderma: A Forgotten Disease
Chancriform pyoderma is a rare condition of uncertain etiology, with intense inflammatory response, producing a lesion that resembles syphilitic chancre. The lesion can be found on the face, especially around the eyelids, near and in the mouth, or on the genitalia.1–5 To our knowledge, this is the first case of chancriform pyoderma located on the hand. Clinically, papules or pustules appear on the affected skin, rapidly enlarging and progressing to painless ulceration. Regional lymph nodes are enlarged and tender, but it is not a rule. The role of S. aureus is still controversial. An abnormal immune response of the host tissues has been postulated. If left untreated, the ulcer may persist for weeks or months to spontaneously involute with or without scarring. Treatment with local and systemic antibiotics is not efficient. According to our experience, differential diagnosis is wide and includes a large group of diseases which contain ulceration in their evolution (Table). Therefore, case history and recognition of other general and specific findings are important for correct diagnosis. The diagnosis of chancriform pyoderma is based on detailed disease history, clinical picture, and negative laboratory findings for all microbial agents except S. aureus. Exclusion of other dermatoses that present with an ulcer, using direct examination, cultures, serology, and histopathology is of greatest importance.
chanciform pyoderma; therapy
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nije evidentirano
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