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Propranolol Use in Heart Failure (CROSBI ID 54751)

Prilog u knjizi | ostalo

Samardžić, Jure Propranolol Use in Heart Failure // Propranolol: Medical Uses, Mechanisms of Action and Potential Adverse Effects / Puljević, Mislav (ur.). New York (NY): Nova Science Publishers, 2015. str. 61-74

Podaci o odgovornosti

Samardžić, Jure

engleski

Propranolol Use in Heart Failure

Propranolol, a first generation nonselective beta blocker, has not been adequately tested in heart failure. Use of beta blockers in general was once absolutely contraindicated in patients with congestive heart failure due to their negative inotropic characteristics. Strong evidence of clinical benefit was shown in large randomized trials with several newer cardioselective beta blockers (bisoprolol, metoprolol, carvedilol, nebivolol) in patients with heart failure. These trials have made beta blockers a standard of care in treating chronic heart failure. Beta blockers do not show a class effect and propranolol is not recommended in heart failure. This chapter explains the rationale for the use of beta blockers in heart failure. It reviews scientific and expert literature dealing with this issue with a focus on trials investigating the efficacy and safety of administrating propranolol in different types of cardiomyopathies and heart failure. Using propranolol in certain conditions such as hypertrophic obstructive cardiomyopathy or co- existing uncontrolable ventricular tachycardias should be considered.

propranolol, beta blockers, heart failure, cardiomyopathy

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Podaci o prilogu

61-74.

objavljeno

Podaci o knjizi

Propranolol: Medical Uses, Mechanisms of Action and Potential Adverse Effects

Puljević, Mislav

New York (NY): Nova Science Publishers

2015.

978-1-63483-004-1

Povezanost rada

Kliničke medicinske znanosti