engleski

Genes involved in maintaining the bone marrow stroma are dysregulated in patients with myelofibrosis: Lenalidomide treatment up-regulates SOCS3

The purpose of our study was to determine whether genes involved in the organisation of the stem cell nice were dysregulated in patients with primary myelofibrosis. Our finding suggests that treatment with lenalidomide plus prednisone up-regulates SOCS3 while several other genes show aberrant expression.

SOCS3; primary myelofibrosis; lenalidomide

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