The impact of population differentiation on statistical forensic parameters of STRs in the South-Eastern Europe region (CROSBI ID 626411)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Novokmet, Natalija ; Marjanović, Damir ; Havaš Auguštin, Dubravka ; Šarac, Jelena ; Šarić, Tena ; Škaro, Vedrana ; Projić, Petar ; Vidovič, Maruška ; Missoni, Saša ; Rudan, Pavao
engleski
The impact of population differentiation on statistical forensic parameters of STRs in the South-Eastern Europe region
The presence of physical and cultural barriers to gene flow influences genetic differentiation between two localized subpopulations. Specifically, isolation of a population from its neighbors by geographical barriers such as the sea reduces genetic interactions between the populations and leads to higher RST values. Furthermore, the presence of certain cultural barriers to gene flow, and social practices such as endogamy, also result in increased levels of population differentiation. In this study the data obtained by the analysis of 9 autosomal STR loci in Croatian islands and Slovenian populations were integrated with the published data from other Croatian islands and wide SE European region. The sample was defined hierarchically and the influence of isolation of the Croatian islands subpopulations on substructuring of the population of Croatia, as well as the influence of the regional population groups on substructuring of South- Eastern Europe was detected. Due to the decreased influence of endogamy, lower genetic differentiation was detected at the higher level of grouping of SE European populations (RST = 0, 002) than at the level of sub- populations of Croatia (RST = 0, 005). Finally, the influence of substructuring of the aforementioned levels on the calculation of forensic statistical parameters was determined. It was found that the isolation of Croatian insular populations affects the value of forensic parameters. These findings indicate that adequate sampling of the entire subpopulation is needed to create representative DNA database of genetic STR markers that would reflect all characteristics of its subpopulations.
population isolates; forensic parameters; STR markers; DNA database; South-Eastern Europe
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Podaci o prilogu
127-127.
2015.
objavljeno
Podaci o matičnoj publikaciji
9th ISABS Conference on Forensic, Anthropologic Genetics and Mayo Clinic Lectures in Individualized Medicine
Kayser, Manfred ; Ördög Tamas ; Vuk-Pavlović, Stanimir ; Primorac, Dragan ; Schanfield, Moses
Zagreb: International Society for Applied Biological Sciences (ISABS)
Podaci o skupu
9th ISABS Conference on Forensic, Anthropologic Genetics and Mayo Clinic Lectures in Individualized Medicine
poster
01.01.2015-01.01.2015
Bol, Hrvatska