engleski

Co-morbidities and age differences in patients hospitalized for acute decompensated chronic heart failure - does it really matter?

Purpose: To analyse co-morbidities in two age groups of patients, hospitalized with acute decompensated chronic heart failure (ADCHF). Methods:We performed single-centre retrospective study of patients consecutively hospitalized for ADCHF. The study was approved by the institution’s Ethics Committee. The retrospective analysis included 1534 patients older than 18 years, enrolled in a Department of Cardiovascular Diseases, from June 2006 to June 2012. Only patients discharged alive were included in further analysis. The patients were divided in two groups according to their age (1340<85 and 194 ≥ 85 years old). We have considered the following comorbidities: arterial hypertension (AH), diabetes mellitus (DM), peripheral arterial disease (PAD), cerebrovascular disease (CVD), ischemic heart disease (IHD) and anaemia. The difference between two groups according to their co-morbidities and possible impact of c-morbidities on the length of hospitalization was analyzed. In all tests P value of <0, 05 was considered statistically significant. Results: The mean patients age in both groups was 74.7 ±10.1 years, in those <85 was 72.8±9.3 years and in ≥ 85 was 88.0±2.7 years (P<0.001). There were 917 (68.4%) patients with AH<85 years versus 152 (78.3%) ≥ 85 years (P=0.005). Likewise, 535 (39.9%) patients<85 years had DM versus 60 (30.9%) ≥85 years (P=0.016). In patients <85 years there were 75 (5.6%)with PAD versus 4 (2.1%) ≥85 years (P=0.037). In patients <85 years 315 (23.5%) had one, 410 (30.6%) had two, 334 (24.9%) had three, 140 (10.4%) had four and 29 (2.2%) had five co-morbidities, while in patients ≥85 years, 39 (20.1%) had one, 71 (36.6%) had two, 64 (33.0%) had three and 11 (5.7%) had four co-morbidities (P=0.003). The length of hospital stay was 10.8±6.1 days for patients <85 years and 10.2±9.1 for those ≥85 years old (P=0.293). Conclusion: There was statistically significant difference according to AH, DM and PAD between the analyzed groups, but there was no statistical difference between groups according to CVD, IHD and anaemia. The difference, considering the number of co-morbidities between age groups, was found to be statistically significant. Data from the literature show that co-morbidities could extend the length of hospitalization in patients with heart failure. However, in the analyzed groups of patients co-morbidities did not affect the length of stay (P>0.005).

chronic heart failure ; age ; co-morbidities ; treatment ; prognosis

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