engleski

Mechanochemical Ritter reaction: A rapid approach to functionalized amides at room temperature

A fast and efficient mechanochemical Ritter reaction be- tween alcohols and nitriles under mild conditions is demon- strated. The reaction proceeds rapidly at room temperature in a solvent-free or low-solvent environment by using a Brønsted acid catalyst. Its general application has been veri- fied through a substrate screening comprising a wide range of functionalized nitriles as well as secondary and tertiary alcohols. Introduction

mechanochemistry; Ritter reaction; organocatalysis; Bronsted acid

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