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Pregled bibliografske jedinice broj: 769190

The role of mood in irritable bowel syndrome symptom severity and quality of life

Pletikosić, Sanda; Tkalčić, Mladenka; Hauser, Goran
The role of mood in irritable bowel syndrome symptom severity and quality of life, 2015. (sažetak u časopisu).

The role of mood in irritable bowel syndrome symptom severity and quality of life

Pletikosić, Sanda ; Tkalčić, Mladenka ; Hauser, Goran

Journal of Psychosomatic Research

Vrsta, podvrsta
Ostale vrste radova, sažetak u časopisu


Ključne riječi
Irritable bowel syndrome ; mood ; quality of life

Background: Irritable bowel syndrome is one of the most common functional gastrointestinal disorders with complex and diverse aetiology. There is a great number of possible factors related to the onset and progression of the disorder. The goal of this study was to test the role of mood in symptom severity and health related quality of life of irritable bowel syndrome patients. Methods: A total of 49 patients (age M=45, 11 ; SD=14, 01 ; F=38) participated in the study and completed a set of questionnaires examining trait anxiety (STAI-T), depression (BDI-II), neuroticism and extraversion (BFI), general (SF-36) and disease specific health related quality of life (IBS- 36). The participants also kept a diary of their mood (PA and NA), symptom severity and daily stressful events for 2 weeks, and their faecal calprotectin levels were determined based on one sample. Findings: The results of regression analyses show that symptom severity and disease specific quality of life could not be predicted based on any of the included variables. However, calprotectin levels and depression were significant predictors of the physical component of SF-36, while positive mood and depression were significant predictors of the mental component of SF-36. Cross- correlation analyses showed that participants whose positive mood was less variable had weaker relationships of symptom severity and daily stress levels. Path analyses showed that depression was a direct predictor of quality of life and an indirect predictor of symptom severity, via daily stressful events. Discussion: Mood seems to have a significant effect on both quality of life and symptom severity of IBS patients. High levels of depression are related to lower quality of life and higher symptom severity, while positive mood is related to higher quality of life and its stability has an impact on the relationship of stress and symptom severity. This would imply that interventions focused on the patients' mood could improve not only their quality of life, but also help in alleviating their symptoms.

Izvorni jezik

Znanstvena područja
Kliničke medicinske znanosti, Psihologija


Projekt / tema
009-0092660-2655 - Psihosomatski aspekti kroničnih funkcionalnih i upalnih bolesti crijeva (Mladenka Tkalčić, )

Filozofski fakultet, Rijeka,
Medicinski fakultet, Rijeka,
Klinički bolnički centar Rijeka