engleski

Regenerative therapy of intrabony periodontal defect using bone substitute material and hyaluronic acid

Aim: Our aim was to achieve regeneration in intrabony periodontal defect using a bone substitute material, deproteinized bovine bone mineral (DBBM) combined with cross-linked hyaluronic acid gel (HA) to improve clinical outcome. Material and Methods: A female patient was referred to our Dental Polyclinic Zagreb, with a bleeding and discomfort around lower right premolar region. During clinical examination and by measuring periodontal indices patient was diagnosed with generalized chronic periodontitis. Proper oral hygiene instructions were explained to the patient and non-surgical periodontal therapy was performed. Reevaluation after two months revealed residual pocket around the tooth 45, measuring 7 mm mesial, 6 mm buccal and 7 mm lingual. We decided to do a regenerative surgical procedure to eliminate residual pocket and manage the intrabony periodontal defect. A modified papilla preservation technique was used which revealed a wide 3-wall defect on the tooth 45. We decided to use a combination of DBBM and HA, with HA being used both as a membrane and with DBBM in a 50:50 ratio. Results: Periodontal pocket around the tooth 45 was probably induced with occlusal trauma, so prior to surgery we adjusted the occlusion. Since HA is a major component of the extra-cellular matrix in almost all tissues, especially periodontal ligament, we decided to take advantage of its biocompatibility, bacteriostatic and anti-inflammatory effect, as well as its potential for regeneration of soft and hard tissues. Conclusion: After 6 months control periapical radiograph was taken which showed bone fill of the intrabony periodontal defect and we measured a reduction of pocket depth from 7 mm to 4 mm.

periodontal regeneration ; intrabony defect ; hyaluronic acid

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